BSGOU

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BSGOU

Bioinformatics Study Group in Okayama University

User-friendly bioinformatics analysis software

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Bioinformatics oriented study

In this bioinformatics-oriented study, we re-analyzed a publicly available RNA-seq dataset complemented by literature mining. This approach identified mitochondria and the cytoskeleton as the primary targets of O-GlcNAcylation in osteoblasts. By cross-referencing multiple databases (O-GlcNAcAtlas, TFLink, and Ensembl Variation), we constructed a gene regulatory network to identify candidate transcription factors (TFs) involved in O-GlcNAcylation-regulated osteogenesis. Guided by our bioinformatics findings, we assessed morphological changes in mitochondria and the cytoskeleton following Ogt knockout.

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About BSGOU

Bioinformatics Study Group in Okayama University (BSGOU) is an international academic community committed to advancing the digital transformation of biological and biomedical research. We unite students, researchers, clinicians, and engineers to collaboratively explore how high-throughput data and integrative computation can drive new theories, models, and discoveries in life sciences.

Click here to check the detailed "Vision and Strategic Plan" of BSGOU

Core Values

Transdisciplinary Collaboration

We unite biology, medicine, engineering, and more to solve complex biological problems together.
Theory-Driven Understanding

We go beyond data analysis to build new models that explain biological complexity.
Open Innovation

We support open science, open-source development, and community collaboration.
Global Inclusivity

We welcome diverse members from all backgrounds and career stages.
Education for Empowerment

We offer training and mentorship to bridge global skill gaps in bioinformatics.
Scientific Integrity and Responsibility

We uphold ethical practices, reproducibility, and responsible data use.
Visionary Leadership

We lead the field with bold ideas and forward-looking strategies.
Serve the People

We aim not only to advance science but also to serve public health through bioinformatics.

Gallery of Our Works

“We believe bioinformatics is not merely a set of tools, but a transformative lens through which biology becomes computable, testable, and deeply understood.”

---- Dr. WANG Ziyi
“BSGOU has transformed my research. The user-friendly software make advanced bioinformatics accessible, even for beginners. I highly recommend BSGOU to anyone seeking practical, powerful tools for scientific discovery.”

---- Dr. WENG Yao

News

Our work has been reposted by official twitter of Keyence Company

October 22, 2024

Keyence Company: "We love seeing how our customers use the BZ-X Series Fluorescence Microscope! If you are using the BZ-X for any research, please share what you are doing & tag us! If you are interested in learning about the BZ-X microscope, contact us at lifescience@keyence.com".
O-GlcNAcylation: a morphological regulator of osteoblast differentiation

October 16, 2024

With AI assistance, our new research published in BioFactors reveals how O-GlcNAcylation controls osteoblast differentiation by reshaping mitochondria, the cytoskeleton, and the endoplasmic reticulum.